BDBM604038 US11660293, Example 142

SMILES C[C@@H]1C2CC(C2)N(C1COc1ccc(F)cc1)C(=O)c1cc(ccc1-n1nccn1)C#N

InChI Key InChIKey=QFSRAZBOABSZSR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 604038   

TargetOrexin/Hypocretin receptor type 1(Human)
Chronos Therapeutics

US Patent
LigandPNGBDBM604038(US11660293, Example 142)
Affinity DataKi:  100nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
Chronos Therapeutics

US Patent
LigandPNGBDBM604038(US11660293, Example 142)
Affinity DataKi:  468nMAssay Description:CHO cells stably transfected with human Orexin type 1 receptors (CHO-hOX1) or HEK-293 cells transiently transfected with human Orexin type 2 receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2023
Entry Details
Go to US Patent