BDBM605286 US11667652, Example 81
SMILES COC1CN(CCO[C@H]2\C=C\[C@H](OC)[C@@H]3CC[C@H]3CN3C[C@@]4(CCCc5cc(Cl)ccc45)COc4ccc(cc34)C(=O)N=[S@@](=O)(C[C@H]2C)NC(=O)c2cn(C)nc2OC)C1
InChI Key InChIKey=QOOQNXHMEPTGGI-CZVUSIIMSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 605286
TargetBcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327](Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 0.0110nMAssay Description:Inhibition of the MCL1 and Bim interaction was measured in the following AlphaLISA assay.Recombinant human MCL1 protein (C-terminal 6×His Tagged MCL1...More data for this Ligand-Target Pair