BDBM609729 DOTA[(Gd(III)]- HyBz-D-Ala- boroPro::US11707539, Compound 5183

SMILES C[C@@H](NC(=O)c1ccc(NNC(=O)CN2CCN3CCN4CCN(CC2)CC(=O)O[Gd](OC(=O)C3)OC(=O)C4)cc1)C(=O)N1CCC[C@H]1B(O)O

InChI Key InChIKey=ZHPLOOABVYXWII-UHFFFAOYSA-K

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 609729   

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609729(US11707539, Compound 5183 | DOTA[(Gd(III)]- HyBz-D...)
Affinity DataIC50: 5.30nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM609729(US11707539, Compound 5183 | DOTA[(Gd(III)]- HyBz-D...)
Affinity DataIC50: 68nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetProlyl endopeptidase(Human)
Tufts College

US Patent
LigandPNGBDBM609729(US11707539, Compound 5183 | DOTA[(Gd(III)]- HyBz-D...)
Affinity DataIC50: 910nMAssay Description:The purpose of this assay is to determine the IC50 of various inhibitors against recombinant human dipeptidyl peptidase IV (DPPIV), fibroblast activa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent