BDBM610107 2-(2-((4-(3-(aminomethyl)phenyl)-1-phenyl-1H-indol-6-yl)methoxy)phenyl)acetic Acid::US11708347, Compound 351f

SMILES NCc1cccc(c1)-c1cc(COc2ccccc2CC(O)=O)cc2n(ccc12)-c1ccccc1

InChI Key InChIKey=MSWIPMVAFZQZKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 610107   

TargetComplement factor D(Human)
Biocryst Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 610107BDBM610107(US11708347, Compound 351f | 2-(2-((4-(3-(aminometh...)
Affinity DataIC50: 1.00E+4nMAssay Description:An established esterolytic assay for the measurement of Factor D activity and inhibition of Factor D activity was used. For this assay Z-Lys-SBzl, 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent