BDBM610924 Methyl {[4-(2,6-dimethoxyphenyl)-5-(5-methylfuran-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}(naphthalen-1-yl)acetate::US10626096, Example 37

SMILES COC(=O)C(Sc1nnc(-c2ccc(C)o2)n1-c1c(OC)cccc1OC)c1cccc2ccccc12

InChI Key InChIKey=VIJHKVUJGOVTMM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 610924   

TargetApelin(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM610924(US10626096, Example 37 | Methyl {[4-(2,6-dimethoxy...)
Affinity DataEC50:  825nMAssay Description:The apelin receptor agonist activity of the compound represented by formula (I) or (II) of the present invention was measured by cell-based assay for...More data for this Ligand-Target Pair
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Date in BDB:
9/8/2023
Entry Details
US Patent