BDBM611504 (2S)-N-[[2-(dimethylamino)-6- [2-hydroxy-4- (trifluoromethyl)phenyl]- pyrimidin-4-yl]methyl]-1-(5- fluorobenzofuran-2- yl)sulfonyl-azetidine-2- carboxamide::US10626112, Example 398

SMILES CN(C)c1nc(CNC(=O)[C@@H]2CCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cc(n1)-c1ccc(cc1O)C(F)(F)F

InChI Key InChIKey=NBXIDUBSUOEAOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 611504   

LigandPNGBDBM611504((2S)-N-[[2-(dimethylamino)-6- [2-hydroxy-4- (trifl...)
Affinity DataIC50: 21nMAssay Description:The test substance was dissolved in dimethyl sulfoxide and serially diluted with an assay buffer containing 0.1% bovine serum albumin (1×HBSS, 20 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
US Patent