BDBM612362 BDBM612608::BDBM612609::N'-((3-fluoro-2,6- diisopropylphenyl)carbamoyl)-2- (2-hydroxypropan-2-yl)thiazole- 5-sulfonimidamide::US11724992, Example 62

SMILES CC(C)c1ccc(F)c(C(C)C)c1NC(=O)N=S(N)(=O)c1cnc(s1)C(C)(C)O

InChI Key InChIKey=LTTVLBFOKNKMRT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 612362   

LigandPNGBDBM612362(N'-((3-fluoro-2,6- diisopropylphenyl)carbamoyl)-2-...)
Affinity DataIC50: 120nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612362(N'-((3-fluoro-2,6- diisopropylphenyl)carbamoyl)-2-...)
Affinity DataIC50: 120nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent

LigandPNGBDBM612362(N'-((3-fluoro-2,6- diisopropylphenyl)carbamoyl)-2-...)
Affinity DataIC50: 3.00E+3nMAssay Description:THP-1 cells were purchased from the American Type Culture Collection and sub-cultured according to instructions from the supplier. Prior to experimen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2023
Entry Details
US Patent