BDBM613324 4-[(2R)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxy-propyl]-8-propanoyl-2,3-dihydro- 1,4-benzoxazepin-5-one::US11725001, Example 214

SMILES CON(C)C(=O)c1ccc2c(OCCN(C[C@H](O)CN3CCc4ccccc4C3)C2=O)c1

InChI Key InChIKey=QGYQJVQYLGXTOY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 613324   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Sk Biopharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 613324BDBM613324(US11725001, Example 214 | 4-[(2R)-3-(3,4-dihydro-1...)
Affinity DataIC50: 550nMAssay Description:The histone H4 peptide was diluted with carbonate-bicarbonate buffer and prepared to 100 μg/mL, and then dispensed onto the plate per 100 μ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2023
Entry Details
US Patent