BDBM614902 A7-59 rac-2-cyano-2-((3R,4R)-4-(((6- (ethyl(4- (trifluoromethyl)benzyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3- hydroxypiperidin-1-yl)acetamide::US20230271937, Example A7-59

SMILES CCN(Cc1ccc(cc1)C(F)(F)F)c1ncnc(NC[C@@H]2CCN(C[C@H]2O)C(C#N)C(N)=O)c1F

InChI Key InChIKey=ZRLCCYONVYXFGE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614902   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 614902BDBM614902(US20230271937, Example A7-59 | A7-59 rac-2-cyano-2...)
Affinity DataEC50:  14nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent