BDBM614909 A7-66-1 rel-(R)-2-((3R,4R)-4-(((6-(ethyl(4- (trifluoromethyl)benzyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3- hydroxypiperidin-1-yl)-3- hydroxypropanamide OR rel-(R)-2-((3S,4S)-4-(((6-(ethyl(4- (trifluoromethyl)benzyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3- hydroxypiperidin-1-yl)-3- hydroxypropanamide 1st eluting major isomer::US20230271937, Example A7-66-1

SMILES CCN(Cc1ccc(cc1)C(F)(F)F)c1ncnc(NC[C@@H]2CCN(C[C@H]2O)[C@H](CO)C(N)=O)c1F

InChI Key InChIKey=NZLQWCRSWOSDDP-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614909   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 614909BDBM614909(US20230271937, Example A7-66-1 | A7-66-1 rel-(R)-2...)
Affinity DataEC50:  26nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent