BDBM614916 Synthesis of rac-2-((3R,4R)-4-(((6-(ethyl(4-(1-methyl-1H-pyrazol-4-yl)benzyl)amino)-5-fluoropyrimidin-4-yl)amino)methyl)-3-hydroxypiperidin-1-yl)acetamide, A7-72::US20230271937, Example A7-72

SMILES CCN(Cc1ccc(cc1)-c1cnn(C)c1)c1ncnc(NC[C@@H]2CCN(CC(N)=O)C[C@H]2O)c1F

InChI Key InChIKey=GQDBCCQOQVTIGZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 614916   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 614916BDBM614916(US20230271937, Example A7-72 | rac-2-((3R,4R)-4-((...)
Affinity DataEC50:  52nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent