BDBM614932 B4-1-1-1 rel-2-((3R,4R)-4-(((6- (cyclopropyl(4- (trifluoromethyl)benzyl)amino)-5- fluoropyrimidin-4- yl)amino)methyl)-3-hydroxy-3- methylpiperidin-1-yl)acetamide 1st eluting isomer::US20230271937, Example B4-1-1-1::US20230271937, Example B4-1-2-1

SMILES CC1(O)CN(CC(N)=O)CC[C@H]1CNc1ncnc(N(Cc2ccc(cc2)C(F)(F)F)C2CC2)c1F

InChI Key InChIKey=DPTMYRKEOWBSLJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 614932   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 614932BDBM614932(US20230271937, Example B4-1-1-1 | B4-1-1-1 rel-2-(...)
Affinity DataEC50:  42nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nuevolution

US Patent
LigandChemical structure of BindingDB Monomer ID 614932BDBM614932(US20230271937, Example B4-1-1-1 | B4-1-1-1 rel-2-(...)
Affinity DataEC50:  55nMAssay Description:The HEK293 cell line is co-transfected transiently with two plasmids, one with the RORγ ligand-binding domain fused to galactose-responsive tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
US Patent