BDBM618426 4-(2-(4-(5-(difluoromethyl)-1,3,4-oxadiazol-2-yl)-2,6-difluorobenzyl)-2H-tetrazol-5-yl)-2-(morpholine-4-carboxamido)phenyl morpholine-4-carboxylate::US20230286970, Compound 196

SMILES FC(F)c1nnc(o1)-c1cc(F)c(Cn2nnc(n2)-c2ccc(OC(=O)N3CCOCC3)c(NC(=O)N3CCOCC3)c2)c(F)c1

InChI Key InChIKey=VHASYGHNGRLMBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 618426   

TargetHistone deacetylase 6(Human)
Italfarmaco

US Patent
LigandPNGBDBM618426(US20230286970, Compound 196 | 4-(2-(4-(5-(difluoro...)
Affinity DataIC50: 107nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
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TargetHistone deacetylase 1(Human)
Italfarmaco

US Patent
LigandPNGBDBM618426(US20230286970, Compound 196 | 4-(2-(4-(5-(difluoro...)
Affinity DataIC50: 2.00E+5nMAssay Description:For each test compound, 100× concentrated DMSO solutions at 8 doses were prepared and then diluted in assay buffer (25 mM Tris-HCl, pH 8, 130 mM NaCl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2023
Entry Details
Go to US Patent