BDBM618572 US11760761, Compound A-1::US11760761, Compound B-1

SMILES COc1cc(cc2CC[C@H](NCC(O)=O)c12)-c1cccc(c1Cl)-c1cccc(c1Cl)-c1cnc(CN2CC3(C2)CCC(=O)N3)c(OC)n1

InChI Key InChIKey=BBRFZXBEZJIFGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 618572   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Aligos Therapeutics

US Patent
LigandPNGBDBM618572(US11760761, Compound B-1 | US11760761, Compound A-...)
Affinity DataIC50: 10nMAssay Description:Compounds to be tested were serially diluted in DMSO, and further diluted in assay buffer (25 mM Hepes pH 7.4, 150 mM NaCl, 0.005% Tween 20, BSA 0.01...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
US Patent

TargetProgrammed cell death 1 ligand/protein 1(Human)
Aligos Therapeutics

US Patent
LigandPNGBDBM618572(US11760761, Compound B-1 | US11760761, Compound A-...)
Affinity DataIC50: 10nMAssay Description:Compounds to be tested were serially diluted in DMSO, and further diluted in assay buffer (25 mM Hepes pH 7.4, 150 mM NaCl, 0.005% Tween 20, BSA 0.01...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2023
Entry Details
US Patent