BDBM619405 US20230295130, Example T-29::US20230295130, Example T-51

SMILES COC(=O)Nc1ccc2c(-c3nc(N[C@H]4CCC[C@@H](O)C4)ncc3C(F)(F)F)c[nH]c2c1Br

InChI Key InChIKey=HHSHHGDJAFPGAP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 619405   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 619405BDBM619405(US20230295130, Example T-51 | US20230295130, Examp...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetCyclin-K/Cyclin-dependent kinase 12(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 619405BDBM619405(US20230295130, Example T-51 | US20230295130, Examp...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 619405BDBM619405(US20230295130, Example T-51 | US20230295130, Examp...)
Affinity DataIC50: 500nMAssay Description:1) The compound solution and the positive control were diluted 8.3 times with double distilled water and then added to the 384 well plate, each conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 619405BDBM619405(US20230295130, Example T-51 | US20230295130, Examp...)
Affinity DataIC50: 500nMAssay Description:1) The compound solution and the positive control were diluted 8.3 times with double distilled water and then added to the 384 well plate, each conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Tyk Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 619405BDBM619405(US20230295130, Example T-51 | US20230295130, Examp...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2023
Entry Details
US Patent