BDBM620225 US20230295171, Example 85

SMILES Cc1cccc(Nc2nc(N[C@@H]3CCOC[C@@H]3N)cc3CNC(=O)c23)c1

InChI Key InChIKey=QJZVPOAVHOGBBL-LSDHHAIUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 620225   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM620225(US20230295171, Example 85)
Affinity DataIC50:  3.98nMAssay Description:YK protein is prepared from cDNA encoding human spleen tyrosine kinase and is expressed in insect cells using a baculovirus expression vector. The cD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent