BDBM625601 US20230322822, Control compound 1
SMILES COc1cc(N2CCC(CC2)N2CCN(C)CC2)c(C)cc1Nc1ncc(Cl)c(Nc2cccc(C)c2P(C)(C)=O)n1
InChI Key InChIKey=ILAMEGXSIDAMQS-UHFFFAOYSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 625601
TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 156nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 160nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 166nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 180nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 184nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 250nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4(Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 250nMAssay Description:To assess the effect of compounds on the activity of EML4-ALK kinases, kinase activity was tested by measuring ATP consumption in an enzymatic reacti...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,T790M](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 250nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [T790M,L858R](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 250nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 250nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-18,20-1210,C797S](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 250nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R,C797S](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 573nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R,T790M,C797S](Human)
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Chengdu Di''Ao Jiuhong Pharmaceutical Factory
US Patent
Affinity DataIC50: 626nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:To assess the effect of compounds on the activity of wild-type and mutant EGFR kinases, kinase activity was tested by measuring ATP consumption in an...More data for this Ligand-Target Pair