BDBM627134 5-(5-Aminoindolin-1-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one hydrochloride::US11787802, Example 140

SMILES Nc1ccc2c(c1)CCN2c1ccc2[nH]c(=O)[nH]c2c1

InChI Key InChIKey=QRYUEFSCINEJTP-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 627134   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
C4 Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 627134BDBM627134(US11787802, Example 140 | 5-(5-Aminoindolin-1-yl)-...)
Affinity DataKd:  168nMAssay Description:1) Optimization of measurement parameters to minimize protein consumption and to minimize the dilution effect and the DMSO content2) Titration measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2023
Entry Details
US Patent