BDBM62942 4-Amino-6,8-dimethyl-2-trifluoromethyl-quinoline-3-carbonitrile::4-amino-6,8-dimethyl-2-(trifluoromethyl)-3-quinolinecarbonitrile::4-amino-6,8-dimethyl-2-(trifluoromethyl)quinoline-3-carbonitrile::4-azanyl-6,8-dimethyl-2-(trifluoromethyl)quinoline-3-carbonitrile::MLS000555622::SMR000147339::cid_622172

SMILES Cc1cc(C)c2nc(c(C#N)c(N)c2c1)C(F)(F)F

InChI Key InChIKey=AIGYFVPRVIBIBS-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 62942   

TargetHeat shock factor protein 1(Mouse)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM62942(4-Amino-6,8-dimethyl-2-trifluoromethyl-quinoline-3...)
Affinity DataEC50:  3.15E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2011
Entry Details
PCBioAssay
TargetX-box-binding protein 1(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM62942(4-Amino-6,8-dimethyl-2-trifluoromethyl-quinoline-3...)
Affinity DataIC50: 9.57E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM62942(4-Amino-6,8-dimethyl-2-trifluoromethyl-quinoline-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM62942(4-Amino-6,8-dimethyl-2-trifluoromethyl-quinoline-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay