BDBM631926 US20230348426, Example 196

SMILES COc1cc(F)c([C@@H]2CN(C(=O)[C@H]2NC(=O)c2ccc(Cl)cc2)c2c(Cl)ccn(C)c2=O)c(F)c1

InChI Key InChIKey=YLYPZXRJWONVHG-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 631926   

TargetN-formyl peptide receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM631926(US20230348426, Example 196)
Affinity DataEC50:  5.20nMAssay Description: A mixture of forskolin (5 M final for FPR2 or 10 M final for FPR1) and IBMX (200 M final) were added to 384-well Proxiplates (Perkin-Elmer) pre-dott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
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TargetfMet-Leu-Phe receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM631926(US20230348426, Example 196)
Affinity DataEC50:  160nMAssay Description: A mixture of forskolin (5 M final for FPR2 or 10 M final for FPR1) and IBMX (200 M final) were added to 384-well Proxiplates (Perkin-Elmer) pre-dott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
Go to US Patent