BDBM632005 US20230348426, Example 275::US20230348426, Example 290

SMILES CNC(=O)C(C)Nc1ccnc(N2C[C@H]([C@H](NC(=O)c3ccc(Cl)cc3)C2=O)c2c(F)cc(OC)cc2F)c1C(F)(F)F

InChI Key InChIKey=HTCQCHUMZKTSQN-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 632005   

TargetN-formyl peptide receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM632005(US20230348426, Example 275 | US20230348426, Exampl...)
Affinity DataEC50:  8nMAssay Description: A mixture of forskolin (5 M final for FPR2 or 10 M final for FPR1) and IBMX (200 M final) were added to 384-well Proxiplates (Perkin-Elmer) pre-dott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetfMet-Leu-Phe receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM632005(US20230348426, Example 275 | US20230348426, Exampl...)
Affinity DataEC50:  6.10E+3nMAssay Description: A mixture of forskolin (5 M final for FPR2 or 10 M final for FPR1) and IBMX (200 M final) were added to 384-well Proxiplates (Perkin-Elmer) pre-dott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetN-formyl peptide receptor 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM632005(US20230348426, Example 275 | US20230348426, Exampl...)
Affinity DataEC50:  8.60nMAssay Description: A mixture of forskolin (5 M final for FPR2 or 10 M final for FPR1) and IBMX (200 M final) were added to 384-well Proxiplates (Perkin-Elmer) pre-dott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetfMet-Leu-Phe receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM632005(US20230348426, Example 275 | US20230348426, Exampl...)
Affinity DataEC50:  1.80E+3nMAssay Description: A mixture of forskolin (5 M final for FPR2 or 10 M final for FPR1) and IBMX (200 M final) were added to 384-well Proxiplates (Perkin-Elmer) pre-dott...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent