BDBM634436 9,14-dioxa-4,5,11,19,20-::US20230357269, Example 121

SMILES O=C1NCCOc2ccc3[nH]nc(-c4cnn(CCCO1)c4)c3c2

InChI Key InChIKey=BOEADBYDWLXJPI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634436   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
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US Patent
LigandPNGBDBM634436(US20230357269, Example 121 | 9,14-dioxa-4,5,11,19,...)
Affinity DataIC50: 550nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent