BDBM634456 8-oxa-10,14,19,20-tetraazatetracyclo::US20230357269, Example 141

SMILES O=C1NCCCNc2ccc3[nH]nc(-c4cccc(CO1)c4)c3c2

InChI Key InChIKey=FNUYGLPPNCXBEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634456   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM634456(US20230357269, Example 141 | 8-oxa-10,14,19,20-tet...)
Affinity DataIC50: 550nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent