BDBM634478 14-methyl-8-oxa-10,14,19,20-::US20230357269, Example 163

SMILES C[C@@H]1CCNC(=O)OCc2cccc(c2)-c2n[nH]c3cnc(cc23)N1C

InChI Key InChIKey=AUQGAFNDQIKHIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 634478   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
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US Patent
LigandPNGBDBM634478(US20230357269, Example 163 | 14-methyl-8-oxa-10,14...)
Affinity DataIC50: 10nMAssay Description:LRRK2 Kinase reactions were carried out in 384-well white polystyrene plates in a final volume of 6 μl using ADP-Glo Kinase Assay kit (Promega C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent