BDBM634493 US20230357271, Example a-01-05::US20230357271, Example a-01-26

SMILES CCCOCc1ncc(cn1)-c1ccc2ncc3N[C@H]4CCN(C)[C@@H](C4)C(=O)NCC(F)COc1c2n3

InChI Key InChIKey=ICVQURFYQXRXRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 634493   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Asahi Kasei Pharma

US Patent
LigandPNGBDBM634493(US20230357271, Example a-01-05 | US20230357271, Ex...)
Affinity DataIC50: 1.37nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Asahi Kasei Pharma

US Patent
LigandPNGBDBM634493(US20230357271, Example a-01-05 | US20230357271, Ex...)
Affinity DataIC50: 1.41nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
Go to US Patent