BDBM634521 US20230357271, Example a-01-19::US20230357271, Example a-01-41

SMILES CN1CC[C@H]2C[C@H]1C(=O)NCC(F)COc1c(ccc3ncc(N2)nc13)-c1cnc(C)nc1

InChI Key InChIKey=BODPAJXKGHCIRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 634521   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Asahi Kasei Pharma

US Patent
LigandPNGBDBM634521(US20230357271, Example a-01-19 | US20230357271, Ex...)
Affinity DataIC50: 1.60nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Asahi Kasei Pharma

US Patent
LigandPNGBDBM634521(US20230357271, Example a-01-19 | US20230357271, Ex...)
Affinity DataIC50: 10nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2024
Entry Details
US Patent