BDBM636039 (1R,2S)-2-(3-{[6-(methanesulfonyl)-2-methoxypyridin-3-yl]amino}-1H-indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indol]-2'(1'H)-one::US20230365537, Example 168::US20230365537, Example 227
SMILES COc1ccc2c(c1)[C@]1(C[C@H]1c1ccc3c(Nc4ccc(S(C)(=O)=O)nc4OC)n[nH]c3c1)C(=O)N2
InChI Key InChIKey=TZKMWKXQVXWVFE-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 636039
Affinity DataIC50: 1.97nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Affinity DataIC50: 2.21nMAssay Description:Activity of human recombinant PLK4 (ThermoFisher, cat #PV6396) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo Kinase...More data for this Ligand-Target Pair
Affinity DataIC50: 521nMAssay Description:Activity of human recombinant Aurora B (ThermoFisher, cat #PR9210B) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Activity of human recombinant Aurora B (ThermoFisher, cat #PR9210B) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Affinity DataIC50: 1.86E+3nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair
Affinity DataIC50: 2.03E+3nMAssay Description:Activity of human recombinant Aurora A (ThermoFisher, cat #PR5935A) was measured by quantification of adenosine diphosphate (ADP) using the ADP-Glo K...More data for this Ligand-Target Pair