BDBM637201 US20230382904, Compound 121::US20230382904, Compound 131::US20230382904, Compound 132

SMILES CC(C)NC(=O)c1cc(cn2nc(N)nc12)-c1csc(c1)C(=O)NC1CC(C)(C)Oc2ccccc12

InChI Key InChIKey=IUHHKZYWPMOFAH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 637201   

TargetProtein delta homolog 1(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM637201(US20230382904, Compound 121 | US20230382904, Compo...)
Affinity DataIC50: 17nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetProtein delta homolog 1(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM637201(US20230382904, Compound 121 | US20230382904, Compo...)
Affinity DataIC50: 28nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetProtein delta homolog 1(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM637201(US20230382904, Compound 121 | US20230382904, Compo...)
Affinity DataIC50: 63nMAssay Description:Assay Protocol for 1536 MTP format: test compounds were predispensed (60 nl) in test plates; +3 μl DLK solution (10 nM DLK, catalytic domain, Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM637201(US20230382904, Compound 121 | US20230382904, Compo...)
Affinity DataIC50: 520nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM637201(US20230382904, Compound 121 | US20230382904, Compo...)
Affinity DataIC50: 730nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 13(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM637201(US20230382904, Compound 121 | US20230382904, Compo...)
Affinity DataIC50: 1.50E+3nMAssay Description:Assay Protocol for 384 low volume MTP format: 1 μl of test compound was pipetted into test plate; +5 μl LZK solution (10 nM LZK, catalytic ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent