BDBM639596 2-[[6, 7-Dichloro-3-(1H-pyrazol-4-yl)-1H-indol-4-yl]amino]ethanol::US20230391786, Example 62

SMILES OCCNc1cc(Cl)c(Cl)c2[nH]cc(-c3cn[nH]c3)c12

InChI Key InChIKey=FLIWPNVADQSPLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639596   

TargetCyclic GMP-AMP synthase(Human)
Eli Lilly

US Patent
LigandPNGBDBM639596(US20230391786, Example 62 | 2-[[6, 7-Dichloro-3-(1...)
Affinity DataIC50: 15.1nMAssay Description:In vitro inhibition assay of cGAS activity: Add a 5 μL mixture containing 10 mM Tris-Cl pH 7.5, 50 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.01% Triton X...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
US Patent