BDBM639760 2-[4-[6-Chloro-3-(1H-pyrazol-4-yl)indol-1-yl]triazol-2-yl] ethanol::US20230391786, Example 229

SMILES OCCn1cc(nn1)-n1cc(-c2cn[nH]c2)c2ccc(Cl)cc12

InChI Key InChIKey=QSRKTYRYHMFUNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 639760   

TargetCyclic GMP-AMP synthase(Human)
Eli Lilly

US Patent
LigandPNGBDBM639760(US20230391786, Example 229 | 2-[4-[6-Chloro-3-(1H-...)
Affinity DataIC50: 96.5nMAssay Description:In vitro inhibition assay of cGAS activity: Add a 5 μL mixture containing 10 mM Tris-Cl pH 7.5, 50 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.01% Triton X...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2024
Entry Details
Go to US Patent