BDBM640154 2-Ethylsulfanyl-4-{6-[2-(6-fluoro-benzofuran-5-yl)-ethylamino]-pyrimidin-4- yl}-benzoic acid::US11839613, Example 275

SMILES CCSc1cc(ccc1C(O)=O)-c1cc(NCCc2cc3ccoc3cc2F)ncn1

InChI Key InChIKey=QBCACCMNMMUMNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 640154   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640154(2-Ethylsulfanyl-4-{6-[2-(6-fluoro-benzofuran-5-yl)...)
Affinity DataIC50: 102nMAssay Description:The SF295 cells (NCI/No. 0503170) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2024
Entry Details
US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640154(2-Ethylsulfanyl-4-{6-[2-(6-fluoro-benzofuran-5-yl)...)
Affinity DataIC50: 468nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2024
Entry Details
US Patent