BDBM640339 US11839613, Example 482::rac-2-(4 -{6-[2-(4-Fluoro-benzo[b]thiophen-5-yl)-ethylamino]- pyrimidin-4-yl}-2-propyl-phenyl)-propionic acid

SMILES CCCc1cc(ccc1C(C)C(O)=O)-c1cc(NCCc2ccc3sccc3c2F)ncn1

InChI Key InChIKey=VGGZQFWGLQQXBO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640339   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM640339(rac-2-(4 -{6-[2-(4-Fluoro-benzo[b]thiophen-5-yl)-e...)
Affinity DataIC50: 323nMAssay Description:The BT549 cells (NCI/No. 0507282) are detached from culture dishes with a cell dissociation buffer (Invitrogen, 13151-014), and collected in growing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2024
Entry Details
US Patent