BDBM640718 US20230399319, Example 2-275

SMILES Cc1ccc(C)c(Nc2nc(co2)C(=O)NS(=O)(=O)N2CCCN(CC2)c2ncccn2)c1

InChI Key InChIKey=FLYCWEMDMFDQQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 640718   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Japan Tobacco

US Patent
LigandPNGBDBM640718(US20230399319, Example 2-275)
Affinity DataIC50: 160nMAssay Description:The NLRP3 inflammasome inhibitory activity of test compounds were evaluated CM the basis of the inhibitory activity of the IL-1β, production in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent