BDBM643284 US20240002388, Compound 93

SMILES CC(C)n1ncc2cnc(nc12)C(=O)NC1(CC1)c1ccc(c(F)c1F)-c1cncn(C(C)C)c1=O

InChI Key InChIKey=XCCHQUPVLNEUMQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 643284   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643284(US20240002388, Compound 93)
Affinity DataIC50: 35nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643284(US20240002388, Compound 93)
Affinity DataIC50: 148nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM643284(US20240002388, Compound 93)
Affinity DataIC50: 148nMAssay Description:ADP-Glo Kinase kit can be used to measure ADP level in kinase activity assay so as to distinguish the inhibitory effects of different compounds on RI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2024
Entry Details
Go to US Patent