BDBM647566 (1s,3s)-3-(tert-Butoxy)-N-(6-(2-((((1S,2S)-2-hydroxycyclopentyl)oxy)methyl)pyrimidin-5-yl)benzo[d]thiazol-2-yl)cyclobutane-1-carboxamide::US20240025893, Example d-02-01

SMILES CC(C)(C)O[C@H]1C[C@H](C1)C(=O)Nc1nc2ccc(cc2s1)-c1cnc(CO[C@H]2CCC[C@@H]2O)nc1

InChI Key InChIKey=VMBRNNMAIFKXPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647566   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Asahi Kasei Pharma

US Patent
LigandPNGBDBM647566(US20240025893, Example d-02-01 | (1s,3s)-3-(tert-B...)
Affinity DataIC50: 1.83nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
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Date in BDB:
3/19/2024
Entry Details
US Patent