BDBM647610 N-(5-(2-((((1S,2S)-2-Hydroxycyclopentyl)oxy)methyl)pyrimidin-5-yl)-4-methoxypyrazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide::US20240025893, Example e-04-01

SMILES COc1c(ccn2nc(NC(=O)C3CC3)cc12)-c1cnc(CO[C@H]2CCC[C@@H]2O)nc1

InChI Key InChIKey=ZYESAEQPMUGXAH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 647610   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Asahi Kasei Pharma

US Patent
LigandPNGBDBM647610(US20240025893, Example e-04-01 | N-(5-(2-((((1S,2S...)
Affinity DataIC50: 3.74nMAssay Description:For the measurement of the activity of the human IRAK-4 (Invitrogen, Cat. PV3362), phosphorylation of the IRAK-4 peptide substrate (biotin-KKKKRFSFKK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2024
Entry Details
US Patent