BDBM648365 acsmedchemlett.2c00502 OICR 7780A, 18

SMILES Cn1cnc2n(CC(=O)Nc3ccncc3Cl)ncc2c1=O

InChI Key InChIKey=SSYJDXWTHRPQHT-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 648365   

TargetB-cell lymphoma 6 protein [5-128](Human)
Ontario Institute for Cancer Research

LigandChemical structure of BindingDB Monomer ID 648365BDBM648365(acsmedchemlett.2c00502 OICR 7780A, 18)
Affinity DataKd:  6.20E+4nMAssay Description:We used a more sensitive Surface Plasmon Resonance (SPR) assay to quantitate the direct binding affinity of ligands to purified BCL6-BTB dimer. Data...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2024
Entry Details
PubMed
TargetB-cell lymphoma 6 protein [5-128](Human)
Ontario Institute for Cancer Research

LigandChemical structure of BindingDB Monomer ID 648365BDBM648365(acsmedchemlett.2c00502 OICR 7780A, 18)
Affinity DataKd:  6.20E+4nMAssay Description:We used a more sensitive Surface Plasmon Resonance (SPR) assay to quantitate the direct binding affinity of ligands to purified BCL6-BTB dimer.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2024
Entry Details
PubMed
TargetB-cell lymphoma 6 protein [5-128](Human)
Ontario Institute for Cancer Research

LigandChemical structure of BindingDB Monomer ID 648365BDBM648365(acsmedchemlett.2c00502 OICR 7780A, 18)
Affinity DataIC50: 8.00E+4nMAssay Description:To identify small molecule BCL6 inhibitors, we developed a Fluorescence Polarization (FP) assay to assess the ability of ligands to compete with a fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2024
Entry Details
PubMed