BDBM649477 US11891378, Example 7

SMILES c1cc(ccc1CC(=O)N2CCN(CC2)c3ccc(nn3)Cl)C4CC4

InChI Key InChIKey=OKOBREVQPHXIFW-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 649477   

TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649477(US11891378, Example 7)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of PANK3 (unknown origin) using D-[1-14C]pantothenate as substrate incubated for 10 mins in presence of ATP by scintillation counting anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
TargetPantothenate kinase 3(Human)TBA
LigandPNGBDBM649477(US11891378, Example 7)
Affinity DataIC50: 5.80nMAssay Description:The assay is not clearly defined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)