BDBM650046 US20240043427, Example 132

SMILES FC(F)Oc1ccc(nc1)[C@H]1C[C@@H]1c1cc(nn2c(F)cnc12)-c1c[nH]c(=O)[nH]c1=O

InChI Key InChIKey=QXWXUZHJMYKLIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 650046   

Target5'-nucleotidase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM650046(US20240043427, Example 132)
Affinity DataIC50: 1.21nMAssay Description:Compound serial dilutions were pre-spotted into Thermo Nunc assay plate. 50 uL CD73 enzyme buffer (CD73 purchased from R&D system=0.6 nM, 25 mM Tris,...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent