BDBM651145 US20240043470, Compound 3-01

SMILES CC(=O)N[C@H]1Cc2cccc(OC\C=C\C[C@H](NC(=O)[C@H](CCc3ccccc3)NC1=O)C(=O)NCC(F)(F)F)c2

InChI Key InChIKey=DTRQWCOQUOZOAL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 651145   

TargetProteasome subunit beta type-5(Human)
Cornell University

US Patent
LigandPNGBDBM651145(US20240043470, Compound 3-01)
Affinity DataIC50: 780nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent

TargetProteasome subunit beta type-8(Human)
Cornell University

US Patent
LigandPNGBDBM651145(US20240043470, Compound 3-01)
Affinity DataIC50: 1.56E+4nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
Go to US Patent