BDBM651191 US20240043470, Compound 3-46-A::US20240043470, Compound 3-46-B

SMILES Fc1ccccc1CNC(=O)[C@@H]1CCCCOc2cccc(CCC(=O)N[C@@H](CC(=O)N3CCCC3C3CC3)C(=O)N1)c2

InChI Key InChIKey=QVGIFHDCHFYUMA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 651191   

TargetProteasome subunit beta type-5(Human)
Cornell University

US Patent
LigandPNGBDBM651191(US20240043470, Compound 3-46-B | US20240043470, Co...)
Affinity DataIC50: 72.3nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetProteasome subunit beta type-8(Human)
Cornell University

US Patent
LigandPNGBDBM651191(US20240043470, Compound 3-46-B | US20240043470, Co...)
Affinity DataIC50: 68nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetProteasome subunit beta type-5(Human)
Cornell University

US Patent
LigandPNGBDBM651191(US20240043470, Compound 3-46-B | US20240043470, Co...)
Affinity DataIC50: 1.35E+3nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent

TargetProteasome subunit beta type-8(Human)
Cornell University

US Patent
LigandPNGBDBM651191(US20240043470, Compound 3-46-B | US20240043470, Co...)
Affinity DataIC50: 312nMAssay Description:Experiments to determine IC50 values against β5i and β5c for compounds were carried out in 96-well plates. In brief, 1 μL of compound ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2024
Entry Details
US Patent