BDBM651718 N-(2-hydroxyethyl)-2- ((6-isopropylbenzo- [d]oxazol-2-yl)amino)- 1-methyl-1H-benzo[d]- imidazole-5-carbox- amide::US20240051952, Example 61

SMILES CC(C)c1ccc2nc(Nc3nc4cc(ccc4n3C)C(=O)NCCO)oc2c1

InChI Key InChIKey=ZYZMMBMJJHQYME-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651718   

TargetHeme oxygenase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM651718(US20240051952, Example 61 | N-(2-hydroxyethyl)-2- ...)
Affinity DataEC50:  1.50E+3nMAssay Description:Measurement of HMOX1 ( HO-1 ) 1. In a polypropylene 384 well plate, human HO-1(after reconstitution in PBS+0.5% Triton+1 mM EDTA) was serially dilute...More data for this Ligand-Target Pair
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Date in BDB:
4/23/2024
Entry Details
US Patent