BDBM651778 2-((5-fluoro-6-(trifluoro- methyl)benzo[d]oxazol- 2-yl)amino)-N-(2- hydroxyethoxy)-1- methyl-1H-benzo[d]- imidazole-5-carbox- amide::US20240051952, Example 130

SMILES Cn1c(Nc2nc3cc(F)c(cc3o2)C(F)(F)F)nc2cc(ccc12)C(=O)NOCCO

InChI Key InChIKey=ZDSGIBDTUPVKJY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 651778   

TargetHeme oxygenase 1(Human)
Mitobridge

US Patent
LigandPNGBDBM651778(US20240051952, Example 130 | 2-((5-fluoro-6-(trifl...)
Affinity DataEC50:  740nMAssay Description:Measurement of HMOX1 ( HO-1 ) 1. In a polypropylene 384 well plate, human HO-1(after reconstitution in PBS+0.5% Triton+1 mM EDTA) was serially dilute...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
US Patent