BDBM652436 6-N-{[6-(piperidin-4-ylmethoxy)pyridin-3-yl]methyl}isoquinoline-1,6-diamine::US20240059691, Example 1016

SMILES Nc1nccc2cc(NCc3ccc(OCC4CCNCC4)nc3)ccc12

InChI Key InChIKey=VKKMVMGDZKPRBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652436   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652436BDBM652436(US20240059691, Example 1016 | 6-N-{[6-(piperidin-4...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent