BDBM652440 3-chloro-N-((6-((1-methylpiperidin-4-yl)methoxy)pyridin-3-yl)methyl)-1H-pyrrolo[2,3- b]pyridin-5-amine::US20240059691, Example 1020

SMILES CN1CCC(COc2ccc(CNc3cnc4[nH]cc(Cl)c4c3)cn2)CC1

InChI Key InChIKey=WMRSPOUNCCDVIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652440   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652440BDBM652440(US20240059691, Example 1020 | 3-chloro-N-((6-((1-m...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent