BDBM652446 US20240059691, Example 1026::{6-[({6-[(1-methylpiperidin-4-yl)methoxy]pyridin-3-yl}methyl)amino]isoquinolin-4- yl}methanol

SMILES CN1CCC(COc2ccc(CNc3ccc4cncc(CO)c4c3)cn2)CC1

InChI Key InChIKey=IOHSRLBIWRWOHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652446   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652446BDBM652446(US20240059691, Example 1026 | {6-[({6-[(1-methylpi...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent