BDBM652451 6-N-({6-[3-(imidazol-1-yl)propoxy]pyridin-3-yl}methyl)isoquinoline-1,6-diamine::US20240059691, Example 1031

SMILES Nc1nccc2cc(NCc3ccc(OCCCn4ccnc4)nc3)ccc12

InChI Key InChIKey=ODERHBIXDZNQHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652451   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652451BDBM652451(US20240059691, Example 1031 | 6-N-({6-[3-(imidazol...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent