BDBM652515 2-ethyl-N-((6-(((1-methylpiperidin-4-yl)methyl)amino)pyridin-3-yl)methyl)-1H- pyrrolo[2,3-b]pyridin-4-amine::US20240059691, Example 1239

SMILES CCc1cc2c(NCc3ccc(NCC4CCN(C)CC4)nc3)ccnc2[nH]1

InChI Key InChIKey=ZJZOLACNWITWKJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652515   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652515BDBM652515(US20240059691, Example 1239 | 2-ethyl-N-((6-(((1-m...)
Affinity DataIC50: 2.50E+4nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent