BDBM652623 5-N-[(2-chloro-4-{[(1-methylpiperidin-4-yl)oxy]methyl}phenyl)methyl]-5-N- methylisoquinoline-1,5-diamine::US20240059691, Example 2203

SMILES CN(Cc1ccc(COC2CCN(C)CC2)cc1Cl)c1cccc2c(N)nccc12

InChI Key InChIKey=FJCDXLHVUXGHIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652623   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652623BDBM652623(US20240059691, Example 2203 | 5-N-[(2-chloro-4-{[(...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent