BDBM652630 N-(1-aminoisoquinolin-6-yl)-4-{[(1-methylpiperidin-4- yl)oxy]methyl}benzenesulfonamide::US20240059691, Example 2210

SMILES CN1CCC(CC1)OCc1ccc(cc1)S(=O)(=O)Nc1ccc2c(N)nccc2c1

InChI Key InChIKey=LEWOAOIBZOMNAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 652630   

TargetCoagulation factor XII(Human)
Kalvista Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 652630BDBM652630(US20240059691, Example 2210 | N-(1-aminoisoquinoli...)
Affinity DataIC50: 650nMAssay Description:In vitro inhibition of Factor XIIa was determined using an IC50 assay based on standard literature methods (see e.g Baeriswyl et al., ACS Chem. Biol....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent